Qwixx: the Card Game captures the spirit of Qwixx - with players still trying to cross off numbers in four colored rows as best they can - but this game uses cards instead of dice, allowing for more tactics and planning as you draft and play a hand of cards.

As in the original game, in Qwixx: the Card Game each player has a scoresheet with the numbers 2-12 in rows of red and yellow and the numbers 12-2 in rows of green and blue. You want to mark off as many numbers as possible, but you can mark off a number only if its to the right of all marked off numbers in the same row. The deck has 44 cards, eleven in each color numbered 2-12; the back of each card shows the number but without the color. Each player starts with a hand of four cards, and four other cards are laid out face-down - that is, with the color hidden - in a row beside the remaining deck of cards.

For a variant, Qwixx: the Card Game includes eleven multicolored joker cards, also numbered 2-12, that are shuffled into the deck. A player determines the color of this card only when playing it on her turn.