Launched as a sequel to Prototype from 2009, Prototype 2 for PS3 has been published by Activision and developed by Radical Entertainment. Released in April 2012, the game involves Sgt. James Heller who is on a quest to destroy Alex Mercer, the lead character in the original Prototype. Heller had lost his entire family during the outbreak of the Blacklight virus. The Prototype 2 game continues 14 months later when Sgt. James Heller returns to New York City where he once lived. He returns to the city after being dismissed from a battle in the Middle East. On reaching the city and discovering the loss of his daughter and wife, he heads on a mission into the Red Zone with the goal of eliminating as many of his enemies he encounters.

As Sgt. James Heller travels to the Red Zone, he loses his entire team on one mission. He then meets Alex Mercer in the Prototype 2 PlayStation 3 game and a fight begins between both of them. After this fight, Mercer manages to infect Heller with the Blacklight virus, his own strain, as he believes Heller would be ideal to ensure Blacklight spreads well beyond Manhattan. Some of the improved features in this game include a richer environment, a larger range of animations and actions, better weather and visual effects. This game also provides Heller with a broader range of new weapons which can be attached and removed from vehicles. Play the Prototype 2 PS3 game to relive the thrill of its preqel and get into the middle of all the action as Heller heads out to stop the Blacklight virus.